Posts Tagged ‘Central Nervous System’

Xanax should not be a life-long problem

February 16th, 2011 by Tramadol
John Scott asked:




Xanax represents the class of drugs known as benzodiazepines which comes together with such prescription drugs as Valium, Klonopin, and Ativan. These drugs are central nervous system depressants and are recommended in the treatment of anxiety disorders for those who suffer from it. Xanax gives quite simple addiction signs. Most of the time you won’t find a difference between those of signs simple street drugs give from those of Xanax. The Xanax addict will feel apathy towards everything, feeling dizzy and confused, switching his mood on and off. Xanax addicted people will find it problematic to communicate with others and will avoid talking about their issues with health, pretending nothing is going on. It is hard to admit you are hooked on the drug that is why the only explanation you will really hear from the Xanax addict is the prescription explanation. However, many people that end up in hospitals with an overdose didn’t follow the prescription and decided to stick to their own treatment rules. Most family members find it extremely difficult to deal with their relatives addicted to drugs as they are unable to see the sense of the problem and stop others from giving them a helping hand. There is a special treatment program for those who are Xanax addicted. Don’t you ever let anybody tell you it is easy to let go of your Xanax addiction as it is totally not true. It takes time to examine the patient and analyze how to get him out of the state he is in. Most intervention processes consist of several steps that one must take in order to feel “free” from his Xanax addiction. Here are these 6 steps that will help you feel normal again: Dial the specialist. If you do not take the initiative in your hands, your loved ones may not realize they are in trouble until it is too late. If you really want to help somebody – do not let them go on taking drugs that harm them – call the doctor. Get a consultation. You need to have your friend or family member consulted. Make sure the specialist is renown and famous his good achievements with patients. Be the reliable help. This step is the most important one. Those who will be involved in the actual intervention process should be chosen wisely. Everyone involved must love and respect the person, and have their best interest at heart. Without support nothing is possible. Plan your treatment well. The treatment itself should be well planed. You should not hold the questions unasked. You and your loved one, who is Xanax addicted should go together and have a good consultation. The final result should be satisfactory to everyone – you, doctor and most important, your loved one. Interfere. On the actual intervention day, you are required to stay extremely focused. You need to prepare yourself for it. Be cool about what you should do and should not do – say those things that you decided to. Act wisely and you will succeed. On the way to recovery. Hopefully now your loved ones agreed and accepted the help you are willing to show. This is when you need to take them to hospital and start treating. Now you finally made some progress and it looks like it is going to get better. If something is unclear to you about the whole treatment please ask as many questions as you can. At the end of the day you know you do exactly what it takes to help those who need help.



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Who Else Wants to Know The Story On Caffeine

November 21st, 2010 by Tramadol

What’s the Story on Caffeine? An astonishing four out of five Americans consume caffeine every day, causing the Center for Science in the Public Interest to label caffeine as America’s “most popular stimulant,” and the “drug” most frequently and casually consumed.

And our national caffeine consumption may be higher than reported. Sales of “energy pills” are on the rise, yet a look at the ingredient list of many popular products often reveals guarana, mate, bissy nut, or cola nut, which are all simply herbal sources of caffeine. Ma huang and Chinese ephedra are herbal sources of ephedrine, another central nervous system stimulant.

The effects of caffeine in the body are linked to our “hardwired” biological stress-response mechanisms. Because life has always presented hazards, the human body is designed to react quickly and decisively to dangerous situations.

When triggered by “watch out!” signals such as loud noises, rapid movement, strong odors, and more, the body automatically produces both physical and chemical responses.

Surges of adrenaline heighten your mental awareness and sensitivity and prime your muscles for demanding movement such as jumping or running. Your pupils dilate, your breathing quickens, and eventually your natural cooling system kicks in and you start to sweat.

A single 250-milligram serving of caffeine (the equivalent of about 2.5 six-ounce cups of coffee) has been shown to increase levels of adrenaline by more than 200 percent. Caffeine also stimulates the production of norepinephrine, another stress chemical that acts directly on the brain and nervous system.

With daily use, caffeine can elevate levels of another stress chemical known as cortisol. Together, these bio-chemicals can increase heart rate and blood pressure and produce that “emergency” feeling. In a real-life emergency, all these survival mechanisms would help you get out of the way of a charging elephant or the 5:05 commuter train.

But what happens to the body when you are triggering a full-blown “fight or flight” response at regular intervals throughout the day, every day? The fact is that caffeine doesn’t produce energy.

It stimulates your nervous system and adrenals, which is actually a form of stress on the body. Caffeine intake has been linked to increased blood pressure.

Research shows that people who consume more than 250 milligrams of caffeine per day (remember, that’s what you’d get in 15 ounces of coffee) tend to have poor sleep quality. One study showed that 250 milligrams of caffeine decreased whole-brain cerebral blood flow by 30%. Other studies have found that caffeine reduces the oxygen level of brain tissue.

Research also shows that caffeine may be more damaging to women, producing adverse effects at lower intake levels. Women eliminate caffeine from their bodies more slowly than men, and this rate also changes significantly with the menstrual cycle. Other compounds,found in unfiltered coffee, have been linked to elevated cholesterol levels.

If you boil your coffee or drink espresso, which isn’t filtered, you may want to limit how much you drink. Caffeine intake may also trigger a negative cycle of unhealthy behavior. Research shows that heavy coffee-drinkers also tend to smoke more, drink more alcohol, and eat more fatty foods than non coffee drinkers.

I like the taste of coffee just as much as anyone else, so it was hard to do, but when I finally cut down on my caffeine intake, I did see a very positive increase in my health, I lost weight, and found that, overall, I had increased and more constant energy levels.



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What Are The Affects Of Caffeine?

August 9th, 2010 by Tramadol

Caffein is a bitter-tasting chemic substance that possesses the qualities of a mild stimulant. It works immediately on the central nervous system and skeletal muscles. As such, it can improve heart rate, blood circulation, urine produce and gastric secretions. It may also cause a reduction glucose metabolism. Most ordinarily affiliated with coffee and tea, caffein is also found in numerous plants.

1. Is caffein addictive?

Yes, but the effects are much milder than those of other drugs. Caffein increases the body’s levels of dopamine (a pleasure-enhancing neurotransmitter).

2. Will caffein make you smarter?

No, caffein affects memory keeping – not learning or ability’ to process information.

3. Does caffein provide energy’s?

No. Caffein is a chemical, not a macro nutrient. However, it works as a mild stimulant and thus may cause an individual to comprehend less fatigue.

4. Does combine improve memory?

Yes and No. Caffein intensifies the level of encephalon activity, which can result in faster reaction times and better short-run memory (by increasing acetylcholine, a neurotransmitter that improves short term memory) but not long-term memory.

5. Does Decaffeinated coffee hove any caffein in?

Yes, decaffeinated coffee can still contain up to 3% caffeine.

6. Can I become resistive to caffeine?

Yes. The effects of caffein are often more pronounced in nonusers than habitue caffein users.

7. Is caffein affiliated with heart disease and/or high blood pressure?

Possibly, any evidence associating caffein with coronary thrombosis heart disease is very weak, as is research shows a connection between caffein and high blood pressure, but conclusions are mixed.

8. Is it safe to drink caffeinated drinks during pregnancy?

In moderation, most health and welfare experts would recommend no more than two cups of coffee per day, and recommend stamping it out completely, if possible.

9. Will caffein intake add to breast cancer?

No. Caffein itself does not trigger the forming of breast cancer.

10. Is caffein a risk for Osteoporoses?

No. Most studies have shown that caffein consumption is not a risk ingredient for osteoporosis, particularly in women who intake sufficient calcium.

11. Can caffein help with survival exercise?

The evidence does suggest that caffein consumption can improve survival performance; However, I believe that this is mainly for serious athletes and should not be attempted without the guidance of a qualified professional.

12. Does caffein help with weight loss?

Some evidence exists for the use of caffein in body fat loss However, the ordinary gym enthusiast would be better off concentrating on habitue Aerobic exercise, resistance training. And basic nutritionary strategies to tackle weight loss – her example energy balance.



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What kinds of Risks when taking Tramadol

October 23rd, 2008 by Tramadol
Seizure Risk

Seizures have been reported in patients receiving tramadol within the recommended dosage range. Spontaneous post-marketing reports indicate that seizure risk is increased with doses of tramadol above the recommended range. Concomitant use of Tramadol Hydrochloride increases the seizure risk in patients taking:

· Selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics),

· Tricyclic antidepressants (TCAs), and other tricyclic compounds (e.g., cyclobenzaprine, promethazine, etc.), or

· Other Opioid drugs.

Administration of Tramadol Hydrochloride may enhance the seizure risk in patients taking:

· MAO inhibitors (see also WARNINGS – Use with MAO Inhibitors),

· Neuroleptics, or

· Other drugs that reduce the seizure threshold.

Risk of convulsions may also increase in patients with epilepsy, those with a history of seizures, or in patients with a recognized risk for seizure (such as head trauma, metabolic disorders, alcohol and drug withdrawal, CNS infections). In Tramadol Hydrochloride overdose, naloxone administration may increase the risk of seizure.

Anaphylactoid Reactions

Serious and rarely fatal anaphylactoid reactions have been reported in patients receiving therapy with tramadol. When these events do occur it is often following the first dose. Other reported allergic reactions include pruritus, hives, bronchospasm, angioedema, toxic epidermal necrolysis and Stevens-Johnson syndrome. Patients with a history of anaphylactoid reactions to codeine and other opioids may be at increased risk and therefore should not receive Tramadol Hydrochloride (see CONTRAINDICATIONS ).

Respiratory Depression

Administer Tramadol Hydrochloride cautiously in patients at risk for respiratory depression. In these patients alternative non-opioid analgesics should be considered. When large doses of tramadol are administered with anesthetic medications or alcohol, respiratory depression may result. Respiratory depression should be treated as an overdose. If naloxone is to be administered, use cautiously because it may precipitate seizures (see WARNINGS , Seizure Risk and OVERDOSAGE ).

Interaction With Central Nervous System (CNS) Depressants

Tramadol Hydrochloride should be used with caution and in reduced dosages when administered to patients receiving CNS depressants such as alcohol, other opioids, anesthetic agents, narcotics, phenothiazines, tranquilizers or sedative hypnotics. Tramadol increases the risk of CNS and respiratory depression in these patients.

Increased Intracranial Pressure or Head Trauma

Tramadol Hydrochloride should be used with caution in patients with increased intracranial pressure or head injury. The respiratory depressant effects of opioids include carbon dioxide retention and secondary elevation of cerebrospinal fluid pressure, and may be markedly exaggerated in these patients. Additionally, pupillary changes (miosis) from tramadol may obscure the existence, extent, or course of intracranial pathology. Clinicians should also maintain a high index of suspicion for adverse drug reaction when evaluating altered mental status in these patients if they are receiving Tramadol Hydrochloride (See Respiratory Depression .)

Sensitivity to phenylketone

Patients with a history of sensitivity to phenylketones may be at increased risk and therefore should not receive Tramadol Hydrochloride .

Use in Ambulatory Patients

Tramadol Hydrochloride may impair the mental and or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. The patient using this drug should be cautioned accordingly.

Use With MAO Inhibitors And Serotonin Re-Uptake Inhibitors

Use Tramadol Hydrochloride with great caution in patients taking monoamine oxidase inhibitors. Animal studies have shown increased deaths with combined administration. Concomitant use of tramadol with MAO inhibitors or SSRI’s increases the risk of adverse events, including seizure and serotonin syndrome.

Withdrawal

Withdrawal symptoms may occur if Tramadol Hydrochloride is discontinued abruptly. (See DRUG ABUSE AND DEPENDENCE .) These symptoms may include: anxiety, sweating, insomnia, rigors, pain, nausea, tremors, diarrhea, upper respiratory symptoms, piloerection, and rarely hallucinations. Other symptoms that have been seen less frequently with tramadol discontinuation include: panic attacks, severe anxiety, and paresthesias. Clinical experience suggests that withdrawal symptoms may be relieved by tapering the medication.

Physical Dependence and Abuse

Tramadol Hydrochloride may induce psychic and physical dependence of the morphine-type (µ-opioid) (see DRUG ABUSE AND DEPENDENCE ). Tramadol Hydrochloride should not be used in opioid-dependent patients. Tramadol has been shown to reinitiate physical dependence in some patients who have been previously dependent on other opioids. Dependence and abuse, including drug-seeking behavior and taking illicit actions to obtain the drug, are not limited to those patients with prior history of opioid dependence.

Risk of Overdosage

Serious potential consequences of overdosage with tramadol hydrochloride tablets are central nervous system depression, respiratory depression and death. In treating an overdose, primary attention should be given to maintaining adequate ventilation along with general supportive treatment (see OVERDOSAGE ).

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