Posts Tagged ‘Morphine’

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March 20th, 2011 by Tramadol
Crystal Ivory asked:




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This article looks at the best way to test for OxyContin or Vicodin use – an oxycodone urine drug test. Since oxycodone is an opioid like morphine and heroin you might think you could use the same test to find it. This article debunks that misconception and will provide the information you need to choose the right home drug test

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Did you know there are drugs in drinking water? In some cities there were as many as 56 different drugs found in drinking water. The risk to human health could be very grave or very minor. But when combined with the other contaminants in tap-water and the health problems they are known to cause I believe the society might be in trouble

Let’s think about drug rehab centers and what images do you conjure? Resort-like facility or a strict hospital-like setting? Chances are your perception does not cover the entire spectrum of drug treatment centers. Since there are several different types of drug rehabilitation programs available ranging from inpatient outpatient residential short-term and long-term it helps to learn what’s out there and how to choose one

Kids may be most affected by prescription drugs in drinking water according to researchers. Pregnant women could also be affected by drugs in the drinking water as well as other hazardous contaminants that can cause birth defects and miscarriages

Here is a brief outline of what malaria is and the pharmaceutical drugs to treat it and the adverse effects that these drugs can cause. Also an introduction to a new safe simple treatment

EMR Systems are not very old in USA; in fact a significant drop in the usage and sales of EMR Systems was recorded after the HIPPA act 1996 became effective. Practices and individual physicians were shy using EMR Systems to avoid any type of identity and critical personal information complications. Fortunately with the CCHIT [certified electronic medical records] backing and certifying these EMR Systems has encouraged sales and usage of EMR Systems at hospitals and clinics

Taser International has made a name for itself in the non lethal weapons arena by developing a line of products useful for both the private citizen as well as for law enforcement and security professionals and even some military agencies. Tasers have several features which make them ideal for use across a broad spectrum of applications. As part of its commitment to making Tasers less than ideal for criminal situations it makes models which spew hundreds of little markers encoded with the serial number of the weapon from which it was fired



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Kadian Questions And Answers

March 11th, 2011 by Tramadol
drugsfaq asked:




More Kadian questions please visit : DrugsFreeFAQ.com

Is kadian 20mg the best strength of throbbing med to help yourself to and it dont wort?

Was walking and was hit by a car i hurt really bad leg swell up when i walk, hip, final and neck pain bad migrains, to where i cant see and my Dr with the sole purpose treat chronic pain and not acute pain what to do…

Is kadian 20mg (morphine) stronger that percocet 10mg?

Kadian is generally for extended pain it is an extended release formula (of morphine) meaning it is designed to work for a longer period of time. Percocet is more for direct pain containing oxycodone and acetaminophen.

Is skelaxin 800mg not detrimental to bear beside kadian 50mg?

Can hydrocodone be used with either skelaxan 800mg or kadian 50mg? – Hydrocodone can be used w/ Skelaxan. Skelaxan is a muscle relaxer and hydrocodone is a type of pain killer. If you’re not sure what you are allergic to , ask your doctor. Your doctor will know best what you obligation. Please…

What are the side effects to the prescription call kadian?

SIDE EFFECTS: May cause constipation, lightheadedness, dizziness, drowsiness, stomach upset, nausea, and flushing the first few days as your body adjust to the medication. If these symptoms persist or become bothersome, inform your doctor. Notify your doctor if you develop: irregular heartbeats, anxiety, tremors, seizures. In the unlikely event you have an allergic reaction to…

What does kadian(morphine sulfate extended-release) capsule show up as on a drug eyeshade?

What does kadian show up as on a drug screen, does it show as the same thing as most pain drug? I know most of them show up as opiates and I was wondering does it show up as the same or different? Shows up as an opioid. It shows…

Can anyone serve? topic on a possible overdose of Kadian?

I have been using kadian 80 mg , but our pharmasist never had it in stock so she would enjoy to write me a 60 and a 20 2 x daily for chronicpain , so I go use to taking 4 pills total a day , ffinaly our pharmacy finaly started carrying the 80…

I hold herniated discs l4 l5 ands1 would this work for me? and I purloin ox-codone kadian,lyrica,morphine,ultram?

I also have herniated discs at c2 to c6 will this work for me? I have had a number of epidural steroid injections and adjectives the pain meds I am on nothing is working and I have been diagnosed beside fibromyalgia. None of these drugs treat…

I’m taking plentifully of medication… they freshly put me on kadian.. can that affect my time mortal lighter?

that is a ? for doctor, your wasting your time you wont get a more reliable answer on YA than youd get from your dr.

Does limbaugh use any drugs besides oxycontin, hydrocodone, lorcet, xanax, kadian, clondine, norco?

And how much prison time did he do for his illegal purchase of drugs from numerous doctors and his household help? http://www.thesmokinggun.com/archive/rushsearch1.html Please don’t post how you are human being ‘attacked’ in 5 minutes. So what’s your point? People who are addicted to drugs should be offered treatment…

Is it 2009 year is worthy for India ( kadian )?

Y wht is kadian?? Of course, it is good for India, Sonuji! It is with hopes we live. When we review the year at the end of 2009, we will find that, after all, it be not a bad year either. Therefore, you will conclude that, yes, the…

Does taking Kadian, a morpine med engender you giant similar to oxycodone?

- Hi- Here are some sites that will help give you a definitive answer. I go to a Pain Management Clinic for injuries sustained over 20 years ago. I do have to clutch Pain Meds for this, but, never have taken Kadian. Here are the sites. Good luck and take care. Source(s):…

I ‘m visit NY & on Kadian can a PrimeCare doc. contained by NY or PA precribe Kadian? Or do I hold to see backache doc.?

I called some pain management clinics in Elmira NY, and adjectives of them seem to be injections only. I can’t just stop taking it and start taking something else without a doctors guidance. I live surrounded…

Is kadian 20mg (morphine) stronger that percocet 10mg?

Kadian is generally for extended pain it is an extended release formula (of morphine) meaning it is designed to work for a longer period of time. Percocet is more for direct pain containing oxycodone and acetaminophen.

It is Kadian 50mg twice on a daily basis, along beside 8 ten mg Methadone on a daily basis not detrimental within this combination please Mam and sir

I made a mistake in first question, Doctor prescribed 8..10mg methadone daily along with 50mg Kadian twice on a daily basis for neck and arm,shoulders, and muscleand joint Chronic pain for a year and a half presently.



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A New Tool to Help you Recover From Pain Pill Addiction: are you Addicted?

February 4th, 2011 by Tramadol
Jeffrey T Junig asked:




Are you addicted to pain pills? You certainly have company. The cycle of use, dependence, and use is playing out, over and over, in every community across the country. Note that I describe the cycle as ‘use, dependence, use’—a description that is accurate, because in most cases the cycle of dependence starts when you appropriately use medication administered by a person who you trust—your physician.

Pain pills are often called ‘narcotics’–a term that comes from the Greek word ‘narcosis’, or ‘sleep’—because of their sedative effects. Physicians use the word ‘narcotic’ to refer to different things in different situations. For example, when referring to controlled substances, ‘narcotics’ may be used to denote drugs regulated by the Drug Enforcement Administration. An anesthesiologist uses ‘narcotic’ to refer to the portion of the anesthetic that is comprised of drugs that bind to brain ‘opiate receptors’. ‘Opiate’ is another word used by physicians in reference to pain pills. The word comes from ‘opium’, a substance derived from poppies and used to make heroin and morphine. The ‘opiate’ reference is also used for synthetic pain medications that have no connection to poppies or opium save their pain-killing effects.

Most people have heard of ‘endorphins’. Endorphins are produced in the human body, and when released, block pain. Endorphins are often referred to as ‘endogenous opiates’ because of their role in pain sensation, even though they have no relation to poppies or opium, and are structurally quite dissimilar. These natural pain relievers have other functions in the body, roles not relevant to this discussion. Endorphins are one group out of dozens of ‘neurotransmitters’, substances involved in the communication between nerve cells. Endorphins and other neurotransmitters act at ‘receptors’, the receptor being a lock on a nerve cell, and the neurotransmitter being the key that fits in the lock. Amazingly, poppies produce a substance that looks different from the natural key, but that acts like endorphins by fitting the exact same keyhole. That substance—one molecule from the sap of a red flower—has given the human species the ability to ease suffering in countless individuals, and has resulted in the deaths of millions of others.

Over the years scientists have developed synthetic ‘opiates’ with potencies far beyond anything produced by nature. Anesthesiologists use ‘sufentanil’ reduce responses to pain during surgery. Sufentanil is extremely potent; an amount the size of one grain of salt, say one tenth of one milligram, placed on the tongue would cause respiratory arrest in a large man within seconds. More commonly opiates are taken by patients in the form of codeine, hydrocodone (Vicodin), oxycodone (Oxycontin), or hydromorphone (Dilaudid). Prescriptions for these substances are handed out to millions of people each day in response to complaints of pain.

Opiates relieve pain, and work in different areas of the brain to elevate mood, ease tension, give a subjective sensation of warmth, and cause sedation. They can cause nausea and vomiting, particularly in patients who are naïve to them. Finally, they change the response of the brain to low oxygen and high carbon dioxide in the blood, and slow respiration. The most common cause of fatal overdose is respiratory arrest, where the brain stops sending impulses to the diaphragm, and the patient suffocates. This fatal response is most common during sleep, or when opiates are taken in combination with other sedative medications.

Opiates are addictive. There is no way to take them without the body adapting and becoming dependent on them. ‘Tolerance’ to pain medication begins after the first dose, when the ‘locks’ on nerve cells adjust in response to all of the ‘keys’ floating around. With time it takes more and more keys to open enough locks to cause the reaction at the nerve cell. Tolerance is one half of the process of addiction, and is the reason for ‘withdrawal’, the sickness that occurs when tolerance has developed and the drugs, or keys, are taken away. The other half of addiction is so-called ‘psychological’, which I suppose is accurate to a point. For some reason, once something is assigned to the psychological category, it is treated differently by physicians, patients, and the rest of society. ‘Psychological’ does not imply that a person has more control than with a ‘physical’ condition—if anything, things occurring on a psychological level are far more difficult to recognize and treat than are physical conditions. The psychological addiction to opiates also develops very rapidly, and there is little if anything that can be done to prevent it. Psychological addiction is real, and is extremely powerful. The result is a desire to take opiates. The desire may take the form of physical symptoms, such as an increase in pain, and so psychological addiction and physical addictions are intimately connected.

To health systems, time is money. Patient complaints are handled as quickly (and sometimes as superficially) as possible. When a person presents in pain, the first determination is whether the pain is a serious threat to health. The second determination is whether enough tests have been done to identify the cause of the pain. If the first answer is no and the second answer is yes, the goal is to clear out the room for the next patient. There is a clock on the wall and a patient list in the hall, and the list has to be clear before the docs and nurses go home. And so there is the doctor—patients waiting in six rooms, more in the waiting area, and a person in the room complaining of something that isn’t going to kill him/her. And in the doc’s pocket lies a pad of paper. Amazingly, all that the doctor has to do to clear the room is write on the pad and wish the patient well.

That is how addiction starts. Everyone intends well; everyone is honest; everyone is innocent. The patient is not told much about addiction. The patient isn’t told that within a few days, he will have some difficulty stopping the medicine. He isn’t told that after a week when he stops the medicine he will have some diarrhea, he won’t be able to sleep, and he will feel depressed. He isn’t told that the pain that he has might not go away, and so he may get more potent medicine, and so on, and that it will get harder and harder to stop as the medicine gets stronger. I don’t know if the lack of information really matters; most patients would likely take the pain relief medicine now, and worry about the rest later. Besides, the doctor doesn’t seem too concerned…and the patient is correct. The doctor isn’t concerned, because this was a quick case that got him nearly caught up to schedule.

Unfortunately, there are pains that do not go away, even as we patients demand relief. Doctors hate to feel impotent with patients–it is difficult to take a person’s money, and then tell him that there is nothing that can be done. And so prescriptions are written, even when the problem may be complicated, and the best advice to the patient would be ‘learn to live with it’. This phrase angers patients with pain, but sounds intelligent to patients who have struggled to get off opiates. But usually, the person with pain walks out with a prescription. As tolerance develops, the pain comes back, and the patient goes to the doctor again, this time leaving with stronger medication. Tolerance continues, meds are changed, and tolerance develops again. The doctor gets nervous over the situation, realizing that at some point he will not have anything stronger. Suddenly calls to the doctor are not returned, or are returned by a curt nurse who sounds like the patient’s mother. The patient realizes that he is stuck, and becomes depressed. Sound familiar?

It is not your fault. I know about this stuff inside and out—I earned my PhD in Neurochemistry at the Center for Brain Research in Rochester New York, studying drugs that cause addiction and tolerance. I administered opiate medications every day as an anesthesiologist. I literally know everything that there is to know about opiates…expect how to stop taking them. I thought I was smart enough to avoid addiction, but I was wrong—laughably wrong—and the outcome nearly killed me. It is not your fault. To get better, you will need to understand the meaning and truth of that statement. That is difficult for some, but possible for everyone.

My next installment has better news. You can become free. You don’t need to leave your family to go to a far-away rehab center, and you don’t need to go through painful detox and withdrawal. Watch for my next installment, or visit me at my address below. There is a new development in treating people dependent on pain pills, a development that will revolutionize the way that doctors treat addiction.



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Pill Addiction; 3 Ways to Beat an Ultram Addiction

November 2nd, 2010 by Tramadol
Christin Shire asked:




Ultram (tramadol hydrochloride) is a synthetic codeine type of non narcotic pain killer, and although touted as a far less addictive alternative to drugs like vicodin, oxycontin and morphine, tens of thousands of Americans have developed serious dependencies on the drug, and have found that the drug they were prescribed as a safer alternative has a syndrome of detox as severe as many of the more potent pain killers.

Symptoms of detox

Some symptoms of detox are nausea, vomiting, tremors, sweating, chills, anxiety, depression, hallucinations, leg restlessness and even seizures; and the risk of seizures increases when people make an attempt at a cold turkey detox.

Withdrawal pains will begin within a day of cessation of use, and will continue with intensity for three or four days before gradually subsiding over a period of months.

3 ways to get off Ultram

1) Cold Turkey

Some people, with enormous will and a determination to endure the pains of detox, can get through withdrawal after quitting without any attempts to first wean down the dosage. Most people cannot endure these detox pains, and since the risks of seizures increase with a dramatic cessation of use, detoxing without medical supervision is unadvised.

2 Wean yourself off

The most commonly attempted method is to gradually wean yourself off of the pills, reducing the dosage slowly over a period of month, or even years. By slowly tapering down, you minimize the intensity of the detox pains, and you also reduce the risks of seizures. Experts advise cutting down by 50 mg’s and waiting for the sensations of slight detox to subside before making another reduction in daily dose. It’s not at all uncommon to wait weeks between reductions in daily dosage.

As you get closer to your goal of complete abstinence, each 50 mg reduction represents a greater percentage of your total daily dose, and the difficulties in the tapering process intensify. If you find that detox symptoms are too severe, you may wish to reduce the doses by only 25 mgs as you get closer to abstinence.

3 Detox under supervision

You really should not attempt to detox cold turkey on your own. You are unlikely to be successful and the risks of seizures are real. If you do not wish to send months of gradual and uncomfortable detox, you may wish to accelerate the process through a brief but intense medically supervised detox.

Certain pharmaceuticals can minimize the risks of seizures inherent in a complete cessation of use, and by detoxing under medical observation; you may safely end a physical addiction in a mater of days. The long term withdrawal symptoms will endure for months, but the immediate and intense symptoms will have ended with the end of detox.

Recovery is possible

Many people also benefit from a period of drug treatment therapy, whether in or outpatient, after a successful detox off of Ultram.

Whichever method you decide on, consulting with your doctor before attempting the process may increase the safety of withdrawal, and your doctor may also prescribe certain medications to reduce withdrawal discomforts.

If you are using Ultram, but are not yet addicted, be very careful with the seductive temptations of Ultram, and spare yourself a long and uncomfortable period of addiction and then withdrawal.



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Understanding Prescription Drug Addiction

September 3rd, 2010 by Tramadol
Xavier Gallery asked:




The abuse and addiction of prescription medications is a growing problem in the United States. The FDA recently reported that more than 48 million people have abused prescription drugs at least once in their life. Abuse occurs under a number of different scenarios, and these include exceeding the recommended dosage, use of a drug outside of the prescribed intent, and prolonged usage. In most cases, the victim initially uses the drug within the prescribed manner. The problems tend to arise once the body builds a tolerance to the medication. Victims are then tempted to use higher doses to counteract the tolerance. It is at this point where addictions can be formed leading to physical and behavioral changes with the body.

While all medications have the potential to be abused, three categories of medicines are more likely to induce addiction behavior.

Opioids are drugs prescribed for their pain-relieving qualities. Commonly refereed to as narcotics, they include codeine, morphine, and oxycodone. Opioids work by attaching themselves to opioid receptors and blocking the transmission of pain signals to the brain. Because the body builds up a tolerance to opioids, abusers often have to consume increasing quantities to achieve their desired effect. Long-term abuse of opioid prescriptions can lead to significant withdraw symptoms (dizziness, vomiting, sweating, etc).

CNS depressants are used to alleviate anxiety and sleep disorder symptoms. The most commonly prescribed CNS depressants are diazepam, alprazolam, and pentobarbital sodium. These drugs interact with the body by decreasing the activity of the brain in order to produce a calming or drowsy effect. Long-term abuse of CNS depressants can lead to a physical dependence that can be dangerous to brain activity if the drug is withdrawn.

Another commonly abused category of drugs are stimulants. These drugs are prescribed to increase brain activity. Stimulants increase a family of brain neurotransmitters called monoamines, which in turn increases body functions such as heart rate, blood pressure, and glucose production. The effects of these drugs can create a psychological dependence for the user. Consistent abuse can cause dangerous side effects such as paranoia, cardiovascular failure, and seizures.

The key to treating prescription drug abuse is to recognize the problem signs. Doctors and pharmacists must be keen observers of any sporadic activity by their patients. This can include abnormal refill cycles, prolonged symptom complaints, and incessant requests for additional medication. Friends and family members can also play an important role in early detection. Identifying behavioral changes and a perceived reliance on medication are reasons to be concerned. If you are unable to confront the victim directly, report the behavior to their doctor or pharmacist.

More information on prescription drug addiction and available treatment is available on Prescription Addiction.info



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Methadone: to Take Or Not to Take This Anti-narcotic Drug

August 13th, 2010 by Tramadol
Nilutpal Gogoi asked:




KNOWING METHADONE

Methadone is an Opioid. Methadone is synthetic by nature. Methadone is also an analgesic. Methadone is basically recommended for the chronic drug abusers. Methadone has been found to be an ideal medication for the treatment of addiction from narcotic substances. Of late, methadone has been widely recommended for patients suffering from chronic pain. Methadone’s effective action remains for long duration. Moreover, Methadone is quite cheap as well. As per the Single Convention on Narcotic Drugs, methadone is included in the list of Schedule II drug.

METHADONE METABOLISM

There are two reasons as to why Methadone effects last longer than other morphine drugs. First, methadone’s lipid solubility is quite high. Second, methadone metabolism is slow. Most importantly, the dependence incidence of patients is low. Hence, there is less danger of a heroin detoxified patient treated on methadone getting hooked to the synthetic opioid. Methadone keeps intact the analgesic effects from a day to two at the most.

IDEAL FOR DE-ADDICTION UNITS

Methadone is ideal for the de-addiction units particularly because of the life of a methadone dosage. Moreover, methadone can be given by injection or even orally. For instance, a single daily dose of methadone is enough to keep under control any heroin addict for the entire day.

TOLERANCE & DEPENDENCE OF METHADONE

The tolerance and dependence of methadone increases as one keeps on taking more doses of the synthetic opioid. In this aspect, methadone is similar to heroin. However, the tolerance factor as well as the effects (physiological) differs. Still, it has been found that methadone leaves no tolerance to constipation. However, the other opioids do leave tolerance effects on the patients especially with respect to constipation. Mentionably, analgesia tolerance appears in the first month after one starts taking the drug. But, tolerance to nausea, sedation and respiratory depression commences within four days after one takes such medications.

METHADONE & NDMA

There is a close link between methadone and the brain receptor known as NMDA (N-methyl-D-aspartic acid). Methadone can even control tolerance and psychic dependence. This is possible because of its strong reaction against opioid. It is due to this reason that patients taking methadone exhibit lesser withdrawal symptoms than those who are into heroin or morphine. Nonetheless, the methadone withdrawal symptoms linger more than the latter.

THE METHADONE LAUNCHER

Methadone was commercially launched by Eli Lilly and Company, a pharmaceutical company.

THE INVENTORS OF METHADONE

German scientists Methadone Gustav Ehrhart and Max Bockmühl jointly synthesized methadone in 1937. They were in search of an analgesic in the Hoechst-Am-Main (IG Farben) laboratory. Their mission was to invent such an analgesic that would solve the twin problems faced by surgeons during surgical operations.

SOLVING SURGEONS’ SETBACKS

First, surgeries were rather problematic with the then extant analgesics. Secondly, the commonly used analgesics were having a high addiction effect. So, both the German scientists found out that synthetic analgesic which would have low addiction effects on the patients and also would be easier to use. They called it Polamidon or Hoechst 10820.

PATENT RIGHTS

It was on September 11, 1941 that the duo filed for patent rights. The structure of this invention was totally different from and least connected with the opioid alkaloids or morphine. Nonetheless, methadone brings about the same types of effects as heroin or morphine. This is because methadone acts on the opioid receptors. Among the opioids, methadone has the simplest chemical composition.

AMERICAN CHAPTER

The Americans came to know of methadone as an analgesic in 1947, courtesy: Eli Lilly and Company. It then rechristened Polamidon or Hoechst 10820 (methadone) as Dolophine. It was under this registered name that methadone was subsequently registered to Roxane Laboratories. Incidentally, the term ‘Dolophine’ has its roots in the German word Dolphium. The Latin word dolor means ‘pain’ while phine means ‘end’.

In the USA, Dolophine (Methadone) was first manufactured by the St. Louis-based Mallinckrodt pharmaceuticals. It is a subsidiary of the Tyco International Corporation. Mallinckrodt enjoyed the patent up to the early part of the 1990s. It still remains the major manufacturer of methadone. The producers of methadone generic preparations also collect their bulk consignments from Mallinckrodt. Nonetheless, many other pharmaceutical companies also produce and distribute methadone today. Moreover Mallinckrodt sells its typical brand of methadone named Methadose as oral concentrate and dispersable tablets in the United States.

THE HITLER LINK…

There is a belief that the German creators coined the name ‘Dolophine’ as a tribute to Adolf Hitler. The Church of Scientology also buttresses this with the data that the earlier name for this synthetic analgesic was actually ‘Adolophine’ or ‘Adolphine’. To make matters worse, vocal Scientologist and actor Tom Cruise also backed the literature in 2005. He was giving an interview to the Entertainment Weekly. However, the weekly soon came out with a follow-up story which nullified the claim. It is, however, now established that the term ‘Dolophine’ was coined by the American wing of the Eli Lilly Corporation after the World War. What is more, the magazine put the lid on the controversy by proving that the 1970 nomenclature of ‘Adolphine’ (which wasn’t ever used for the drug) was also brought into being in the States.

THE METHADONE ADVANTAGE

The low cost of methadone as well as its effectiveness over a long period of time made it rather popular too. While 30 days dose of the analgesic Demerol cost $ 125 in the fag end of 2004, the equivalent amount of methadone cost $20.

METHADONE COUSINS

There are many drugs similar in composition and effects to methadone. They are Buprenorphine, heroin (diamorphine), ORLAM and dextropropoxyphene.

Buprenorphine and methadone are used in the UK and many other countries for the treatment of narcotic addicts. Heroin is also known as diamorphine. Many countries allow heroin to be prescribed for patients undergoing detoxification programs. Heroin is also given to patients taking treatment for many other opiate addictions.

Interestingly enough, an Austrian study shows that orally tendered morphines are more effective than its oral methadone counterpart. Patients developing immunity to many traditional detoxification programs positively respond to a combination of morphine and a low dosage of methadone.

ORLAM is a synthetic compound. It is also known as LAAM. It is composed of levo-alphacetylmethadol. LAAM ‘s effects last from 42 to 72 hours. This compound was okayed as a medication for the patients suffering from chronic narcotics addiction in 1994. LAAM is also included in the US Controlled Substances Act (Schedule II). After reports were received that LAAM intake caused cardiac complications in some people, it was withdrawn from the American and the European markets.

Dextropropoxyphene is popular as a pain reliever. In the USA, more than 100 ton of this oral analgesic is produced annually. It is most effective in patients suffering moderate pains.

Dextropropoxyphene overdose is reported to have been the cause of many deaths especially among the recreational youth generation. In fact, it is among the top 10 such drugs in the USA. Dextropropoxyphene is included within Schedule II of the US Controlled Substances Act. However, medications containing Dextropropoxyphene are put in the Schedule IV. Its strength can be gauzed from the fact that aspirin takes 600 mg to be equal to just 65 mg of Dextropropoxyphene. It was first marketed in 1957 as Darvon.

METHADONE ABUSE

Methadone abuse is not common primarily because it is not strong. Besides, the addicts prefer such opioids whose effects are instant or fast. In this aspect, methadone is rather slow. But abusers use the snort method to elicit a stronger euphoric and faster effect. There are, of course, occasional reports of deaths occurring due to methadone overdose. Such instances are more among the perennial drug abusers. Such habituated abusers go for methadone species like the ‘Street Meth’. Many illicit drug markets sell methadone as alternatives to other opioids.

METHADONE ABUSERS

Such demands are usually from three types of people. Those addicts who had at one point of time taken methadone as a part of medical regimen may again feel a strong tendency to go for methadone. Moreover, kin of patients having methadone may fall easy prey to the synthetic drug. There can also be a demand for methadone from the habituated opioid abusers if they are unable to get hold of any other brands.

METHADONE ILLICIT MARKET

The methadone consignments enter the illicit drug market via two ways. Methadone packets usually get diverted into the illicit market from the destinations. It can also enter the drug market through theft. This is done mainly from the shippers or from the factories. Such methadone consignments rarely find their ways to the illicit drug market from the patients prescriptions.

THE METHADONE DEBATE

Of late, there has been a growing controversy about the efficacy of methadone. This is notwithstanding its proven track record that methadone is an opioid analgesic. There has been a rise in the number of methadone related deaths around the globe. Many vouchsafe that methadone is intimately connected with the drug abusers. Above all, there has not been a single scientific report that methadone is an ideal medication for relieving chronic pain. One thing is for sure, though. Methadone does not possess any extra-strong pain relieving effects compared to the other opiates. It has, however, been established that methadone is far more dangerous than most opiates. It is for such reasons that many physicians do not encourage methadone use.

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Hydrocodone: Prescription Drug Abuse & Testing

June 1st, 2010 by Tramadol

Hydrocodone or dihydrocodeinone is a semi-synthetic opioid derived from two of the naturally occurring opiates, codeine and thebaine.

Hydrocodone Prescription, Dosage & Administration:

Hydrocodone is an orally active, narcotic analgesic and antitussive. Being a narcotic analgesic, it is prescribed for the relief of moderate to severe pain & being a antitussive, it is prescribed as a medicine used to suppress or relieve coughing.

Hydrocodone comes both as a tablet and also in liquid form & thus can easily be taken orally. 5 mg of hydrocodone is equivalent to 30 mg of codeine when administered orally. Earlier hydrocodone and morphine were considered equipotent for pain control in humans. However, it is now considered that a dose of 15 mg of hydrocodone is equivalent to 10 mg of morphine. Hydrocodone is considered to be morphine-like in all respects and thus, final dosage is adjusted by physician according to the severity of the pain and the response of the patient.

Hydrocodone Abuse:

Vicodin i.e. hydrocodone in combination with acetaminophen, is a commonly abused version of hydrocodone in United States and Canada. Vicodin, as with all narcotic analgesics, can be habit forming—causing dependence, tolerance, and withdrawal symptoms if not used as it is prescribed. The presence of acetaminophen in hydrocodone-containing products deters many drug users from taking excessive amounts.

Effects of Hydrocodone Abuse:

Some of the common side effects of drug abuse include dizziness, lightheadedness, nausea, drowsiness, euphoria, vomiting, and constipation. Some of the lesser common side effects are various allergic reactions, blood disorders, mood swings, mental fogginess, anxiety, lethargy, difficulty in urinating, ureter spasms, rashes and irregular or depressed respiration etc.

Physical Dependence on Hydrocodone:

Opioid analgesics such as Hydrocodone may cause psychological and physical dependence. Physical dependence results in withdrawal symptoms in patients who abruptly discontinue the drug. Physical dependence usually does not occur to a clinically significant degree until after several weeks of continued opioid usage, but it may occur after as little as a week of opioid use.

Commercial Status in United States:

There are over 200 products containing hydrocodone in the U.S. When sold commercially in the US, hydrocodone is always combined with another medication due to a separate federal regulation. In its most usual forms, hydrocodone is combined with acetaminophen. Such commercial hydrocodone products which are combined with acetaminophen are known by various trademark names such as Vicodin & Lortab. Hydrocodone also can be combined with aspirin (Trade name: Lortab ASA), ibuprofen (Trade name: Vicoprofen), & certain antihistamines (Trade name: Hycomine).

Pure Hydrocodone tablets or capsules are not offered currently by any USA drug company. The cough preparation Codiclear DH is the purest available US hydrocodone item, containing guaifenesin and small amounts of ethanol as active ingredients.

With such a huge number of Hydrocodone containing products, the possibility of misuse and addiction remains substantial. As a result, Sales and production of this drug has increased significantly in recent years & so has its diversion and illicit use. To limit abuse of opioid drugs like Dilaudid it is necessary to properly assess the patient, employ proper prescription practices, periodically re-evaluate the opioid therapy, and properly dispense and store the drugs.

Hydrocodone Testing:

Hydrocodone may not cause a positive result in a standard opiate urine test. Many opiate tests test only for morphine (which both codeine and heroin break down into). This is true for both home/business kits and laboratory testing.

However, there are several specialized home and laboratory testing kits available that specifically detects hydrocodone (& hydromorphone, its metabolic product). So test results usually depend on the particular type of test that is used and whether or not laboratory verification is done. If a home drug test is given and the opiate test shows a positive result (due to hydromorphone use), laboratory verification might not result in a positive test because the lab may only test for morphine.



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Pill Addiction; 3 Ways to Beat an Ultram Addiction

September 19th, 2009 by Tramadol

Ultram (tramadol hydrochloride) is a synthetic codeine type of non narcotic pain killer, and although touted as a far less addictive alternative to drugs like vicodin, oxycontin and morphine, tens of thousands of Americans have developed serious dependencies on the drug, and have found that the drug they were prescribed as a safer alternative has a syndrome of detox as severe as many of the more potent pain killers.

Symptoms of detox

Some symptoms of detox are nausea, vomiting, tremors, sweating, chills, anxiety, depression, hallucinations, leg restlessness and even seizures; and the risk of seizures increases when people make an attempt at a cold turkey detox.

Withdrawal pains will begin within a day of cessation of use, and will continue with intensity for three or four days before gradually subsiding over a period of months.

3 ways to get off Ultram

1) Cold Turkey

Some people, with enormous will and a determination to endure the pains of detox, can get through withdrawal after quitting without any attempts to first wean down the dosage. Most people cannot endure these detox pains, and since the risks of seizures increase with a dramatic cessation of use, detoxing without medical supervision is unadvised.

2 Wean yourself off

The most commonly attempted method is to gradually wean yourself off of the pills, reducing the dosage slowly over a period of month, or even years. By slowly tapering down, you minimize the intensity of the detox pains, and you also reduce the risks of seizures. Experts advise cutting down by 50 mg’s and waiting for the sensations of slight detox to subside before making another reduction in daily dose. It’s not at all uncommon to wait weeks between reductions in daily dosage.

As you get closer to your goal of complete abstinence, each 50 mg reduction represents a greater percentage of your total daily dose, and the difficulties in the tapering process intensify. If you find that detox symptoms are too severe, you may wish to reduce the doses by only 25 mgs as you get closer to abstinence.

3 Detox under supervision

You really should not attempt to detox cold turkey on your own. You are unlikely to be successful and the risks of seizures are real. If you do not wish to send months of gradual and uncomfortable detox, you may wish to accelerate the process through a brief but intense medically supervised detox.

Certain pharmaceuticals can minimize the risks of seizures inherent in a complete cessation of use, and by detoxing under medical observation; you may safely end a physical addiction in a mater of days. The long term withdrawal symptoms will endure for months, but the immediate and intense symptoms will have ended with the end of detox.

Recovery is possible

Many people also benefit from a period of drug treatment therapy, whether in or outpatient, after a successful detox off of Ultram.

Whichever method you decide on, consulting with your doctor before attempting the process may increase the safety of withdrawal, and your doctor may also prescribe certain medications to reduce withdrawal discomforts.

If you are using Ultram, but are not yet addicted, be very careful with the seductive temptations of Ultram, and spare yourself a long and uncomfortable period of addiction and then withdrawal.



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Is Tramadol Safe?

August 25th, 2009 by Tramadol

Tramadol is the generic version of Ultram which is a synthetic pain medication with properties that have been known to react similarly to that of morphine. Tramadol is an opiate; therefore it affects the opioid receptors in the brain which are responsible for pain management. Tramadol can be extremely safe if it is taken correctly, for short durations of time, and is monitored by a physician. Normally, Tramadol is prescribed for moderate to severe pain but Tramadol is not as strong as Vicodin or Oxycontins. Because Tramadol is an opiate antagonist its primary job is to alter the way that the body reacts to pain.

Tramadol, when prescribed can be written for immediate release or extended time release. Of course they are available in various milligrams too; normally the immediate release is dispensed as 50 mg and the time release are dispensed in 100 mg, 200 mg, and 300 mg. Usually the time release Tramadol is used for patients who require long term pain management. It is also very important to take Tramadol exactly as directed, which is to be swallowed whole. Chewing them, crushing or splitting them is not recommended and is not safe. Because Tramadol is a member of the opiate family it does have addictive properties and when taken over a long period of time it is quite common to acquire a resistance to it which might make you feel as if the Tramadol is no longer working. Do not increase the amount of Tramadol that you take without consulting your physician and do not just stop taking it either as you will likely experience some unpleasant side effects while in opiate withdrawal. The dose should be professionally decreased gradually.

Tramadol can further be considered safe as long as you are honest with your doctor about the current medications that you might be taking as some can have a detrimental effect when combined with Tramadol such as Carbamazepine, which is normally taken for the treatment of epilepsy or bi polar disorder. The Carbamazepine reduces the effect of the Tramadol. Quinidine which is used for specific heart diseases makes Tramadol about 50-60% stronger than when Tramadol is taken by itself. Taking Tramadol with

MAO (monoamine oxidase inhibitor) inhibitor or SSRI (selective serotonin reuptake inhibitors) can actually cause seizures and other serious side effects. Tramadol should never be used in combination with alcohol, narcotic drugs, anesthetics, tranquilizers, and sedatives. It should also not be taken by pregnant women or nursing mothers.

Of course there are certain side effects associated with taking Tramadol just as there is with any medication. When not mixed with any other drugs that can cause unpleasant side effects, Tramadol is safe to take however, the issue lays with its addictive properties. Many people have been known to literally become addicted over a period of time which can lead to craving stronger opiates. This is why it can not be stressed strongly enough that Tramadol must be taken only when monitored by a physician. Tramadol can be a very effective and safe pain reliever if is taken correctly and monitored so that a dependency does not occur.



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This page is provided for educational and informational purposes only and is not intended as a substitute for the advice of a medical doctor, nurse, nurse practitioner or other qualified health professional.