Posts Tagged ‘Receptors’

Endorphins, the Body’s Natural Pain Killers and Exercise

Nikhil Abraham asked:




Endorphins, the body’s natural pain killers and exercise

The word is derived from endogenous ( inside the body) and morphine( morphine like effect)

Hence , endorphins are chemicals produced by the brain during certain periods that have effects similar to morphine and other opioid drugs. They however, do not cause dependence and addiction like the drugs.

Another significant difference is with regard to the duration of action. Endorphins ( which are made up of smaller subunits of proteins called peptides ) are rapidly degraded by the body’s enzymes unlike externally administered drugs which tend to act for long periods.

Their effect is brought about by activating certain receptors and modifying the transmission of other chemicals that communicate between nerve cells. Endorphins are most commonly released during periods of pain and stress.

In addition to lowering pain, they also have several positive effects on mood and even boost the immune system. This has potential implications in management of precancerous cells and research is going on in this regard.

Mood elevating effects are commonly seen after exercise and is the basis of the term ‘runners high’ .

While the extent of endorphins’ contribution to this is still a matter of debate among scientists, what is clear is that endorphins are found in higher concentration after bouts of exercise.

Typically, half an hour of continuous, moderately intense exercise releases endorphins.

For those less inclined to strenuous athletic activity , there is good news.

Other triggers for endorphin release include eating chocolates or chillies, sex, massage, acupuncture, laughter and meditation.

Its another known fact that endorphin levels differ among people. Apart from resting levels, the amount of activity required or the duration of the response also varies tremendously.

In another promising research area , similar pathways to the endogenous opioid system have been discovered with even more wide ranging effects such as memory , anxiety , sleep and appetite. Potential drugs targeting these areas are of great promise and indeed exciting times are ahead.

We now have yet another reason to exercise regularly. If nothing else, it simply makes us feel good and increases our immunity.

Care must be taken however , not to overdo it. High endurance and intensity exercises done for long periods of time ( for eg. triathlons and marathons ) results in the body also producing steroids to cope with the stress, thereby temporarily decreasing immunity. In such cases , enough time should be given for rest and recovery.

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For Chronic Pain Treatment, Ultram May Work Best

Bill Johnson asked:




Many doctors and physicians put the phrase chronic pain treatment and Ultram in the same sentence because this medicine is now one of the most popular choices for those in chronic and crippling pain. While not treating or curing any disease, when it comes to chronic pain treatment, Ultram is affording patients a great deal of relief from their arthritis or joint pain, and many other causes of pain as well.

How it Works

For chronic pain treatment, Ultram is not a cure for a disease or condition. It does not treat or address the arthritis or back problems that give people chronic pain. What it does is cut off the receptors in the body that translate nerve signals and impulses as pain. It numbs or eases these receptors.

As an example, think of when you put ice on a sore or cut. The ice numbs the nerves at the skin’s surface so that they no longer feel the pain from the injury. Your sore or cut is not being treated or cured with this ice, you simply can’t feel the pain that you should be feeling because of it.

With chronic pain treatment, Ultram works much the same way. It simply numbs the nerve endings so the body does not register that pain any longer. It will not cure your arthritis or your degenerated disk in your back or any other condition that is causing your chronic and constant pain.

Side Effects

When considering whether or not this is the best medication for you personally, it’s important to consider the possible side effects when addressing chronic pain treatment with Ultram. There are many potential side effects to this medicine, including dizziness, numbness, change in mood, sleepiness but with an inability to get to sleep and stay asleep, nervousness and agitation, muscle tightness, and uncontrolled shaking in some parts of the body. However, these side effects are typically rare and mild and most who have them report that they are not going to let them stop taking the medication.

When it comes to chronic pain treatment, Ultram seems to be the best for most patients and is quickly becoming the most prescribed by doctors everywhere. It is strong enough to treat most cases of pain whether it’s from arthritis or another condition and has side effects that seem to be mostly mild and very manageable. While there are of course some concerns and considerations with this chronic pain treatment, Ultram is the choice preferred by most.

For more information from Bill Johnson about Ultram and pain relief please check http://www.ultramhome.com/pain-relief.html



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This page is provided for educational and informational purposes only and is not intended as a substitute for the advice of a medical doctor, nurse, nurse practitioner or other qualified health professional.